کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5594154 | 1571287 | 2017 | 24 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effect of pulmonary hyperinflation on central blood volume: An MRI study
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Pulmonary hyperinflation attained by glossopharyngeal insufflation (GPI) challenges the circulation by compressing the heart and pulmonary vasculature. Our aim was to determine the amount of blood translocated from the central blood volume during GPI. Cardiac output and cardiac chamber volumes were assessed by magnetic resonance imaging in twelve breath-hold divers at rest and during apnea with GPI. Pulmonary blood volume was determined from pulmonary blood flow and transit times for gadolinium during first-pass perfusion after intravenous injection. During GPI, the lung volume increased by 0.8 ± 0.6 L (11 ± 7%) above the total lung capacity. All cardiac chambers decreased in volume and despite a heart rate increase of 24 ± 29 bpm (39 ± 50%), pulmonary blood flow decreased by 2783 ± 1820 mL (43 ± 20%). The pulmonary transit time remained unchanged at 7.5 ± 2.2 s and pulmonary blood volume decreased by 354 ± 176 mL (47 ± 15%). In total, central blood volume decreased by 532 ± 248 mL (46 ± 14%). Voluntary pulmonary hyperinflation leads to â¼50% decrease in pulmonary and central blood volume.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 243, September 2017, Pages 92-96
Journal: Respiratory Physiology & Neurobiology - Volume 243, September 2017, Pages 92-96
نویسندگان
Tanja Mijacika, Kasper Kyhl, Daria Frestad, F. Otto Barak, Ivan Drvis, Niels H. Secher, Zeljko Dujic, Per Lav Madsen,