کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5594181 | 1571294 | 2017 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Impact of sleep disordered breathing on carotid body size
ترجمه فارسی عنوان
تأثیر تنفس ناشی از خواب بر روی اندازه بدن کاروتید
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کلمات کلیدی
آپنه خواب شاخص آپنه ناحیه کمری توموگرافی کامپیوتری، آنژیوگرافی، هیپوکسمی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
چکیده انگلیسی
We tested the hypotheses that: (1) carotid body size can be measured by computed tomographic angiography (CTA) with high inter-observer agreement, and (2) patients with sleep apnea exhibit larger carotid bodies than those without sleep apnea. A chart review was conducted from patients who underwent neck CTA and polysomnography at the Mayo Clinic between January 2000 and February 2015. Widest axial measurements of the carotid bodies, performed independently by two radiologists, were possible in 81% of patients. Intra-class correlation coefficients ranged from 0.93 to 0.95 (Right carotid body: 0.93; Left: 0.94; Average: 0.95). Widest axial measurements of the carotid bodies were greater in patients with sleep apnea (n = 32) compared to controls (n = 46, P-value range 0.02-0.04). After adjusting for age, no differences in carotid body size were observed between the patient groups (P-value range 0.45-0.59). We conclude carotid body size can be detected by CTA with high inter-observer agreement; however, carotid body size is not increased in patients with sleep apnea.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 236, February 2017, Pages 5-10
Journal: Respiratory Physiology & Neurobiology - Volume 236, February 2017, Pages 5-10
نویسندگان
Brian T. Welch, Humphrey G. Petersen-Jones, Andy R. Eugene, Waleed Brinjikji, David F. Kallmes, Timothy B. Curry, Michael J. Joyner, Jacqueline K. Limberg,