کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5790058 | 1553958 | 2015 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immune response of piglets on a PRRSV vaccination-Altered by different feed additives?
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
Animal performance was not affected by the experimental diets. Hematological parameters and complete blood counts displayed time-dependent changes, feed-related effects were not observed. The analysis of the expressed lymphocyte surface markers showed distinct time dependent shifts but no dietary effects. CD4âCD8α+ cells reached highest levels on day 21 post vaccination and decreased thereafter (P=0.037), the CD2+CD5â cells decreased in all groups towards day 35 (P<0.001). CD2+CD5+ cells were determined at constant levels during the observation period, while CD2âCD5+ decreased at day 21 (P=0.039) and CD4+CD8αâ cells decreased over time (P=0.003). CD4+CD8α+-double positive cells increased age-dependently in all groups (P=0.006). CD21+ cells and CD14+ cells were not affected by age. Increasing levels of specific IgG were determined (P<0.001), but group effects could not be demonstrated as for the interferon γ producing T cells. The development of the immune system in piglets seems to follow a typical time-dependent pattern, the lack of dietary effects on the immune response in this trial might be due to a balanced diet and appropriate sanitary conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Livestock Science - Volume 174, April 2015, Pages 96-104
Journal: Livestock Science - Volume 174, April 2015, Pages 96-104
نویسندگان
S. Speiser, L. Scharek-Tedin, A. Mader, A. Saalmüller, W. Gerner, K. Männer, K. Stadler, J. Zentek,