کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5790384 1109492 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of oral caffeine administration to sows with induced parturition on hypoxia in piglets
ترجمه فارسی عنوان
اثرات تجویزی کافئین خوراکی به گاوهای همراه با گاوهای ناشی از هیپوکسی در خوک
کلمات کلیدی
خوک، کاشت تولد منجر به تولد، کافئین، هیپوکسی بچه گانه،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی
To counteract the effects of perinatal hypoxia in piglets, the oral administration of caffeine to sows with induced parturition was evaluated. On day 113 of gestation 9 sows received 27 mg/kg body weight (BW) of caffeine mixed with 200 g of standard diet. The same amount of feed without the addition of caffeine was administered to 9 control sows. Additionally, on day 113 of gestation, all sows were treated by two injections in the perianal area of 1 mg of alfaprostol (at 8:00 am and 14:00 pm), and on the morning of farrowing by 14 IU of oxytocin in the perianal area. Caffeine did not affect BW of piglets and size of litters; however piglets from treated sows showed a higher capacity to adapt to extra-uterine life. Particularly, they showed a greater thermoregulatory ability (P<0.001) and a higher percentage of viability score≥7 compared to piglets from control sows (92% vs. 75%, respectively; P=0.030). Caffeine furthermore reduced the frequency of high serum biopterin values (>80 nmol/L) in piglets born from treated sows (P=0.001). In conclusion, the caffeine orally administered to sows with induced parturition showed a protective effect on the consequences of neonatal hypoxia in tissue ischemia-reperfusion injury in piglets.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Livestock Science - Volume 157, Issue 1, October 2013, Pages 372-377
نویسندگان
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