کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5797975 | 1111766 | 2014 | 7 صفحه PDF | دانلود رایگان |
A randomized clinical trial was conducted to compare the efficacy of rapid intravenous (IV) infusion of a 7.2% hypertonic saline solution with that of continuous application of an isotonic solution in stabilizing the circulation of cows with abomasal volvulus. Cattle treated with hypertonic saline had a significantly greater reduction in volume deficit within the first 10âmin of therapy than cows treated with isotonic saline (from 5.9â±â4.8 to 2.1â±â4.4âL/100âkg vs. 7.0â±â4.5 to 4.9â±â3.8âL/100âkg, respectively). The central venous pressure (CVP) of the cows given the hypertonic saline rose within the first 10 min of therapy from 7.3â±â3.5 to 10.8â±â3.4âcm H2O, while the CVP of the cattle treated with isotonic saline did not increase significantly during this time.Sixty minutes after the start of the infusion, the CVP of the isotonic group was still significantly lower than that of the hypertonic group (9.5â±â2.1 vs. 10.3â±â3.3âcm H2O, respectively). Within the first 60âmin, the base excess decreased from 5.5â±â6.9 to 4.7â±â6.2âmmol/L in the hypertonic group whereas it increased from 5.6â±â5.7 to 6.8â±â5.4âmmol/L in the isotonic group. These results suggest that for cows with abomasal volvulus, IV therapy with hypertonic saline may improve the haemodynamic and circulatory situation considerably faster and more effectively than continuous infusion with isotonic saline.
Journal: The Veterinary Journal - Volume 201, Issue 3, September 2014, Pages 338-344