ENaC mediates human extravillous trophblast cell line (HTR8/SVneo) invasion by regulating levels of matrix metalloproteinase 2 (MMP2)

Aldosterone induced ENaC activity is important for trophoblast cells invasion. The results also indicate that ENaC could mediate trophoblast cells invasion ability through regulating expression and activity of matrix metalloproteinase-2 (MMP2).