کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5895875 1154488 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Effect of Intrauterine Growth Retardation on the Expression of Developmental Factors in Porcine Placenta Subsequent to the Initiation of Placentation
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
The Effect of Intrauterine Growth Retardation on the Expression of Developmental Factors in Porcine Placenta Subsequent to the Initiation of Placentation
چکیده انگلیسی

Intrauterine growth retardation (IUGR) hinders fetal growth and postnatal development in swine; however the etiology of IUGR is essentially unknown. Expression of fourteen candidate genes associated with placental development or IUGR was examined in gestational day 50 (gd50) control and IUGR fetus whole placental tissue or areolae by real-time PCR. Endothelial nitric oxide synthase (ENOS) mRNA expression was elevated in gd50 IUGR placenta and areola compared to gd50 control. Since ENOS could modulate vascular tone and angiogenesis via nitric oxide production, data suggest that the increase in IUGR may be an adaptive response to poor perfusion to maintain pregnancy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Placenta - Volume 31, Issue 6, June 2010, Pages 549-552
نویسندگان
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