Effect of protein-tyrosine phosphatase 4A3 by small interfering RNA on the proliferation of lung cancer

► PTP4A3-siRNA inhibits PTP4A3 expression in lung cancer H1299 cells. ► PTP4A3 siRNA promotes apoptosis of lung cancer cells. ► PTP4A3 gene was correlated with lung cancer cell cycle distribution. ► PTP4A3 plays an important role in the proliferation of lung cancer cells.