A major imprinted gene involved in hydatidiform mole is not located in 2q31.2-qter or 5q34-qter

► A triploid partial mole was seen in a women carrying a balanced translocation t(2;5). ► The mole was disomic androgenetic telomeric to the breakpoint on chromosome 5. ► It is unlikely that a gene causing the complete molar type is located in this region. ► On chromosome 2 the mole had balanced biparental genome telomeric to the breakpoint. ► A gene causing the molar phenotype is unlikely to be located in this region.