کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5922293 1165362 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Steroidal regulation of hydrolyzing activity of the dietary carbohydrates in the silkworm, Bombyx mori
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش حشره شناسی
پیش نمایش صفحه اول مقاله
Steroidal regulation of hydrolyzing activity of the dietary carbohydrates in the silkworm, Bombyx mori
چکیده انگلیسی

Blood sugar is an essential energy source for growth and development and is maintained at a constant level through precise regulation of formation and utilization. Sugars are produced from dietary carbohydrates by enzymatic hydrolysis in the digestive tract, which are under the homeostatic control of paracrine and prandial mechanisms in mammals. Here, we show that dietary carbohydrates hydrolyzing activity of the digestive tract is developmentally regulated by the steroid hormone ecdysone in the silkworm, Bombyx mori. The dietary carbohydrates hydrolyzing activity remained high throughout the last larval period and then decreased to negligible levels until the pupal period. However, dietary carbohydrates digestive activities were constitutively high when the steroidogenic organ, prothoracic glands were ablated. The prothoracic glands produced and released a large amount of ecdysone at the end of the larval period, suggesting that ecdysone is responsible for the decrease in dietary carbohydrates hydrolyzing activity. In fact, ecdysone decreased the activity to negligible levels in silkworms lacking the prothoracic glands. The present results indicate that the dietary carbohydrates hydrolyzing activity is regulated by ecdysone and that an increase in ecdysone titer decreases that activity at the end of the larval period, suggesting that ecdysone is essential for metabolic coordination during development.

Highlights► We focused on hormonal regulation of carbohydrate digestion enzymes of the silkworm. ► The digestive enzymes were developmentally regulated by ecdysone. ► Increase in ecdysone titer decreased enzyme activity at the end of larval period. ► Ecdysone is essential for metabolic coordination during the larval-pupal development.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Insect Physiology - Volume 57, Issue 9, September 2011, Pages 1282-1289
نویسندگان
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