Inhibition of rat carotid body glomus cells TASK-like channels by acute hypoxia is enhanced by chronic intermittent hypoxia

► Chronic intermittent hypoxia (CIH) enhances chemosensory hypoxic response by unknown mechanisms. ► CIH enhanced glomus cells hypoxic responses due to a large and fast inhibition of TASK-like channels. ► This novel effect of CIH may partly explain the enhancing effect of CIH on CB oxygen chemoreception.