Pulmonary arterial systolic pressure and susceptibility to high altitude pulmonary edema

► Pulmonary arterial hypertension plays a major role in high altitude pulmonary edema. ► We measured pulmonary systolic pressure in susceptible and resistant subjects to HAPE. ► No overlap in pulmonary systolic pressure was observed between the 2 groups. ► Pulmonary systolic pressure during a hypoxic exercise challenge may predict HAPE.