Neural control of airway to deep inhalation in rabbits

At Ctrl, RL8 °C and RL4 °C were significantly lower than RL37 °C. After Mch, however, RL4 °C was not different from RL37 °C, both being significantly higher than RL8 °C. Vagal cold block (VCB) abolished the bronchodilation observed after the control DI and reduced its magnitude after Mch. The magnitude of bronchodilation immediately after the DI was significantly related to baseline RL at any vagal temperature (p < 0.001), but the renarrowing was more strongly related to baseline RL after VCB than at baseline. The data indicate a significant contribution of respiratory reflexes to the airway response after DI, highlight the influence of vagal control of airway wall visco-elasticity and suggests the occurrence of a moderate reflex bronchodilation in response to Mch.