Electrochemical biosensor based on CdS nanostructure surfaces

Well-defined hexangularly faced CdS nanorod arrays have been grown directly on a conductive ITO glass via a facile one-step and non-template hydrothermal approach. Gold nanoparticles were decorated onto the nanorods to enhance the electron transfer process of electrode. Glucose oxidase (GOD) was then immobilized on the CdS through crosslinking with chitosan (CS), which resulted in a glucose biosensor with high enzyme loading and excellent sensitivity. Such a chitosan-encapsulated GOD-based biosensor revealed a relatively rapid response time of less than 50 s, and an approximate linear detection range of glucose concentration, from 50 to 500 μmol L−1 with a detection limit of 38 μmol L−1 and an electrode sensitivity of 5.9 μA mM−1.

We have demonstrated a novel glucose sensor based on the highly efficient immobilization of GOD with chitosan on a Au nanoparticles modified ITO–CdS nanorods surface.Figure optionsDownload high-quality image (103 K)Download as PowerPoint slideHighlights
► The CdS is able to efficiently increase the electron transfer reactivity of GOD.
► The Au nanoparticles are deposited to enhance the electron transfer process.
► In addition, chitosan is an efficient redox mediator.