Phase-assisted synthesis and DNA unpacking evaluation of biologically inspired metallo nanocomplexes using peptide as unique building block

► Novel metallo nanocomplexes synthesized via modified Brust-Schiffrin approach. ► Among all the products, zinc and cobalt nanocomplexes unpack the DNA most efficiently. ► Biological inspirations of nanocomplexes are proved by targeting bacterial and fungal strains. ► Biological inspiration of the metallo nanocomplexes is driven by their size and the peptide PrHA.