کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
608454 | 880593 | 2012 | 6 صفحه PDF | دانلود رایگان |

This study constitutes a demonstration of the biological route to controlled nano-fabrication via modular multi-functional inorganic-binding peptides. Specifically, we use gold- and silica-binding peptide sequences, fused into a single molecule via a structural peptide spacer, to assemble pre-synthesized gold nanoparticles on silica surface, as well as to synthesize nanometallic particles in situ on the peptide-patterned regions. The resulting film-like gold nanoparticle arrays with controlled spatial organization are characterized by various microscopy and spectroscopy techniques. The described bio-enabled, single-step synthetic process offers many advantages over conventional approaches for surface modifications, self-assembly and device fabrication due to the peptides’ modularity, inherent biocompatibility, material specificity and catalytic activity in aqueous environments. Our results showcase the potential of artificially-derived peptides to play a key role in simplifying the assembly and synthesis of multi-material nano-systems in environmentally benign processes.
Figure optionsDownload high-quality image (199 K)Download as PowerPoint slideHighlights
► Combinatorially selected inorganic-binding peptides are versatile molecular linkers.
► Peptides control assembly and in situ synthesis of nanometallic particles on surface.
► Tested peptides can functionalize surfaces at ambient conditions.
► Bio-enabled fabrication route offers modularity, flexibility, biocompatibility.
Journal: Journal of Colloid and Interface Science - Volume 365, Issue 1, 1 January 2012, Pages 97–102