Thermo-sensitive amphiphilic supramolecular assembly based on cyclodextrin inclusion

The ionic self-assembled organic microrods are obtained through complexing two functional molecules, sodium deoxycholate and 1-adamantanamine hydro-chloride. Meanwhile, the amphiphilicity of the complex could be changed by a supramolecular approach with cyclodextrin (CD) inclusion to obtain a thermo-sensitive system. The microrod morphology and structure are characterized by optical microscopy, scanning electron microscopy, single crystal analysis and X-ray powder diffraction. The mechanism of thermo-sensitivity induced by β-CD inclusion complex is discussed in view of dynamic balance between the host β-CDs and guest molecules. Experimental results indicate the feasibility of single crystal culture in ionic self-assembly and potential application of CDs in thermo-sensitive supramolecular systems.

Ionic self-assembled organic single crystal is obtained through complexing sodium deoxycholate and 1-adamantanamine hydro-chloride, the amphiphilicity of which is changed by cyclodextrin inclusion to obtain a thermo-sensitive system.Figure optionsDownload high-quality image (62 K)Download as PowerPoint slideResearch highlights
► The ionic self-assembled organic single crystal is obtained.
► Amphiphilicity of the complex could be changed and a thermo-sensitive system is obtained by cyclodextrin (CD) inclusion.
► Salt effect has been studied in the process of single crystal growth.