Spontaneous adsorption of silver nanoparticles on Ti/TiO2 surfaces. Antibacterial effect on Pseudomonas aeruginosa

Titanium is a corrosion-resistant and biocompatible material widely used in medical and dental implants. Titanium surfaces, however, are prone to bacterial colonization that could lead to infection, inflammation, and finally to implant failure. Silver nanoparticles (AgNPs) have demonstrated an excellent performance as biocides, and thus their integration to titanium surfaces is an attractive strategy to decrease the risk of implant failure. In this work a simple and efficient method is described to modify Ti/TiO2 surfaces with citrate-capped AgNPs. These nanoparticles spontaneously adsorb on Ti/TiO2, forming nanometer-sized aggregates consisting of individual AgNPs that homogeneously cover the surface. The modified AgNP–Ti/TiO2 surface exhibits a good resistance to colonization by Pseudomonas aeruginosa, a model system for biofilm formation.

Citrate-capped silver nanoparticles are spontaneously adsorbed on Ti/TiO2 substrates. The silver nanoparticle-modified surfaces exhibit a good antibacterial effect against attached Pseudomonas aeruginosa.Figure optionsDownload high-quality image (92 K)Download as PowerPoint slideResearch highlights
► Simple and efficient method to modify Ti/TiO2 surfaces with silver nanoparticles.
► Silver nanoparticles spontaneously and homogeneously adsorb on Ti/TiO2, forming nanometer-sized aggregates.
► Adsorption of silver nanoparticles is promoted by their citrate capping.
► Modified AgNP–Ti/TiO2 surface exhibits good antibacterial properties against Pseudomonas aeruginosa.