Developmental abnormalities and changes in cholinesterase activity in sea urchin embryos and larvae from sperm exposed to engineered nanoparticles

► Toxicity of Ag, TiO2 and Co NPs was investigated in sea urchin' sperm. ► Sperm functionality, embryos-larvae morphology and enzymatic activity were analyzed. ► Developmental anomalies and altered ChE activity were identified. ► Exposure to NPs may cause neurotoxic damage, and ChE activity may be involved in skeletogenic aberrations. ► Sea urchin represents a sensitive model for testing toxicity of engineered NPs.