Copper(II) chelate-bonded magnetite nanoparticles: A new magnetically retrievable catalyst for the synthesis of propargylamines

In this study, we document the use of a reusable magnetic nanoparticle (MNP)-supported copper catalyst for the efficient synthesis of propargylamines via the A3 coupling of benzaldehydes, phenylacetylene, and piperidine or morpholine. The new MNPs were characterized by scanning electron microscopy, energy dispersive X-ray analysis, Fourier transform infrared spectroscopy, thermogravimetric analysis, and vibrating sample magnetometry. Notably, the activity and leaching test of the catalyst indicated that the MNPs could be reused without loss to its catalytic activity or leaching of its copper ligands.