Exometabolomics and MSI: deconstructing how cells interact to transform their small molecule environment

- We review the entire field of exometabolomics.
- We describe the complementarity of LC-MS and MSI approaches for exometabolomics.
- Mass spectrometry imaging can be used to gain spatial information on the interaction of cells.
- Exometabolomics can be used for phenotype, biofuel, drug and bioprocess development.