Determination of thermodynamic and kinetic properties of biomolecules by mass spectrometry

- We review the processes associated to native electrospray ionization mass spectrometry.
- Native biomolecules in the gas phase is discussed.
- Ion mobility-mass spectrometry applications in biomolecule structure characterization is reviewed.
- Utility of HDX for protein structure elucidation is discussed.
- Binding constant determination by mass spectrometry is reviewed.