Microbial production of amino acids and derived chemicals: Synthetic biology approaches to strain development

- Amino acid producers improved combining classical mutagenesis with metabolite sensors.
- New route to efficient l-proline production established.
- C. glutamicum engineered for lysine production from alternative carbon sources.
- C. glutamicum amino acid producing strains engineered to biotin prototrophy.
- Deamination and decarboxylation yield fermentative access to amino acid-derived products.