Protein engineering of cellulases

- Scarce experimental data drive the importance of computational results in cellulase engineering.
- More and more new helper proteins will aid cellulases in the overall hydrolysis process.
- Both SCHEMA recombination and consensus approach achieved cellulase thermostabilization.
- Four Trp residues in the catalytic domain active site tunnel are linked to processivity.
- Glycosylation of both catalytic domain and linker affect specific activity.