کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6597385 1423852 2018 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance
ترجمه فارسی عنوان
فراوانی آلل، ژنوتیپ و هپلوتیپهای دو پلی مورفیسم در ژن خوسترین در جمعیت سالخورد روسیه با عملکرد شناختی طبقه بندی شده
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
چکیده انگلیسی
This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disease and cognitive functions in genome-wide and candidate genes association studies. Cognitive performance in sample set was estimated by the Montreal Cognitive Assessment (MoCA). The frequencies of alleles, genotypes and haplotypes of two SNPs were calculated in 3 groups: total sample set, sample set with MoCA score less than 21 (the first quartile) and group with MoCA score more than 24 (the fourth quartile).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Data in Brief - Volume 16, February 2018, Pages 775-779
نویسندگان
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