Fast nanoparticle sizing by image dynamic light scattering

• Image dynamic light scattering (IDLS) method was introduced for nanoparticle sizing.
• Real-time acquisition was achieved with a CCD camera.
• Standard latex spheres were tested to verify the feasibility of IDLS method.
• Temperature control unit was not essential in short acquisition time of milliseconds.
• Use of a dispersion medium with high viscosity was recommended.

In this paper, an image dynamic light scattering method for nanoparticle sizing is introduced. The spatial distribution of the scattered lights from nanoparticles undergoing Brownian motion was captured at a high frame rate by a digital camera within one second, which is considerably faster than the conventional photon correlation spectroscopy method. The captured series of photographs were meshed into thousands of small units for calculating the intensity autocorrelation functions in parallel. Experimental results from the measurements of three reference nanoparticle samples (27, 80, and 352 nm in diameters) demonstrated the feasibility of this method.

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