Effect of particle shape and size on flow properties of lactose powders

The shape and size of particles are understood to affect the bulk behaviour of powders, though there are but few studies that present quantitative information on the relationship between particle shape and the flow properties of powder. This is due in part to the lack of techniques for rapidly determining both particle shape and the range of flow characteristics that describe the response of powders to the stress and shear experienced during their processing. This study presents data that quantifies the influence of particle shape/size of three different lactose powders on their respective flow and bulk characteristics. Two of the samples differ in size but have similar shapes; the third sample is more spherical but similar in size to one of the other two samples. The results demonstrate that in addition to particle size, particle shape significantly affect the flow characteristics of a powder over a wide range of stress conditions.

Figure optionsDownload as PowerPoint slideHighlights
► The dynamic, shear and bulk properties of the powders were examined.
► Samples were chosen to allow isolation of particle size and particle shape effects.
► Both particle size distribution and shape significantly affect all flow properties.
► Modification of the shape of powder can alter the flow properties more efficiently.