کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6803421 1433539 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
RAB39B gene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
RAB39B gene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies
چکیده انگلیسی
Mutations in Ras-related protein Rab-39B (RAB39B) gene have been linked to X-linked early-onset Parkinsonism with intellectual disabilities. The aim of this study was to address the genetic contribution of RAB39B to Parkinson's disease (PD), dementia with Lewy bodies (DLB), and pathologically confirmed Lewy body dementia (pLBD) cases. A cohort of 884 PD, 399 DLB, and 379 pLBD patients were screened for RAB39B mutations, but no coding variants were found, suggesting RAB39B mutations are not a common cause of PD, DLB, or pLBD in Caucasian population.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Aging - Volume 45, September 2016, Pages 107-108
نویسندگان
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