کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6915306 1447395 2018 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fluid-structure simulation of a general non-contact tonometry. A required complexity?
ترجمه فارسی عنوان
شبیه سازی ساختار سیال یک تونومتر غیر تماس عمومی. پیچیدگی مورد نیاز؟
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
چکیده انگلیسی
Understanding corneal biomechanics is important for applications regarding refractive surgery prediction outcomes and the study of pathologies affecting the cornea itself. In this regard, non-contact tonometry (NCT) is gaining interest as a non-invasive diagnostic tool in ophthalmology, and is becoming an alternative method to characterize corneal biomechanics in vivo. In general, identification of material parameters of the cornea from a NCT test relies on the inverse finite element method, for which an accurate and reliable modelization of the test is required. This study explores four different modeling strategies ranging from pure structural analysis up to a fluid-structure interaction model considering the air-cornea and humor-cornea interactions. The four approaches have been compared using clinical biomarkers commonly used in ophthalmology. Results from the simulations indicate the importance of considering the humors as fluids and the deformation of the cornea when determining the pressure applied by the air-jet during the test. Ignoring this two elements in the modeling lead to an overestimation of corneal displacement and therefore an overestimation of corneal stiffness when using the inverse finite element method.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computer Methods in Applied Mechanics and Engineering - Volume 340, 1 October 2018, Pages 202-215
نویسندگان
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