کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6915911 862926 2016 44 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Computational modelling of multiscale, multiphase fluid mixtures with application to tumour growth
ترجمه فارسی عنوان
مدل سازی محاسباتی چند محوری، مخلوط مایع چند فازی با کاربرد در رشد تومور
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
چکیده انگلیسی
In this work we consider the discretization of a recently formulated (Collis et al., [22]) multiscale model for drug- and nutrient-limited tumour growth. The key contribution of this work is the proposal of a discontinuous Galerkin finite element scheme which incorporates a non-standard coupling across a singular surface, and the presentation of full details of a suitable discretization for the coupled flow and transport systems, such as that arising in Collis et al. [22] and other similar works. We demonstrate the application of the proposed discretizations via representative numerical experiments; furthermore, we present a short numerical study of convergence for the proposed microscale scheme, in which we observe optimal rates of convergence for sufficiently smooth data.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computer Methods in Applied Mechanics and Engineering - Volume 309, 1 September 2016, Pages 554-578
نویسندگان
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