کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6925280 1448753 2018 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
An efficient 2D implementation of a bio-chemo-mechanical model employing a quadratic representation to study cells on micro-post arrays
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
پیش نمایش صفحه اول مقاله
An efficient 2D implementation of a bio-chemo-mechanical model employing a quadratic representation to study cells on micro-post arrays
چکیده انگلیسی
The paper aims to present an implementation in FEniCS of a bio-chemo-mechanical model which is widely used in modelling mechanical interaction between biological cells and their underlying substrate together with an approach for complexity reduction. The contact behaviour of the cell on the substrate is described using an alternative formulation, where a mixed function space is utilised on a single mesh. The weak form for the equilibrium condition is derived from the principle of virtual work. The methodology and the implementation using the open-source framework FEniCS are described. The results are compared with our previous outcomes using commercial software, where an approach with multiple meshes was used.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Finite Elements in Analysis and Design - Volume 146, July 2018, Pages 16-27
نویسندگان
, , ,