Active targeting co-delivery system based on pH-sensitive methoxy-poly(ethylene glycol)2K-poly(ε-caprolactone)4K-poly(glutamic acid)1K for enhanced cancer therapy

The prepared folate-modified pH sensitive co-delivery system of FA-poly(DOX+VER) polymer assembly exhibits obvious pH-sensitivity, high active targeting ability, strong multidrug resistance reversal and the enhanced therapeutic effect.112