The effect of oil type on the aggregation stability of nanostructured lipid carriers

- NLC suspension stability was strongly affected by the type and amount of carrier oil.
- Triglyceride oils with lower melting temperatures favored stable suspension formation.
- Particles became more spherical as the oil concentration was increased.
- Suspensions could be stabilized at low surfactant concentrations.
- Reduced particle shape change and increased surfactant mobility enhance stability.