Disposition and association of the steric stabilizer Pluronic® F127 in lyotropic liquid crystalline nanostructured particle dispersions

► Association of F127 with cubosomes and hexosomes is driven by F127 concentration. ► F127 association with cubosomes and hexosomes is irreversible. ► Particle nanostructure and lipid type influences association of F127. ► Cubosome particle size is influenced more by the concentration of F127 than lipid.