کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7051083 | 1457255 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Experimental investigation of the effect of non-Newtonian behavior of blood flow in the Fontan circulation
ترجمه فارسی عنوان
بررسی تجربی اثر رفتار غیر نیوتنی جریان خون در گردش فونت
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کلمات کلیدی
LPASVCIVCRPABiofluid dynamicsWall shear stress - استرس برش دیوارsuperior vena cava - بزرگ سیاهرگ بالایی، بزرگ سیاهرگ زبرینCongenital heart disease - بیماری قلبی مادرزادیNon-Newtonian fluid - سیالات غیر نیوتنیright pulmonary artery - شریان ریوی راستLeft pulmonary artery - شریان ریوی چپXanthan gum - صمغ زانتانfontan - فونتنInferior vena cava - پایین پنجه گاو
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
جریان سیال و فرایندهای انتقال
چکیده انگلیسی
The Fontan procedure for univentricular heart defects creates a unique circulation where all pulmonary blood flow is passively supplied directly from systemic veins. Computational simulations, aimed at optimizing the surgery, have assumed blood to be a Newtonian fluid without evaluating the potential error introduced by this assumption. We compared flow behavior between a non-Newtonian blood analog (0.04% xanthan gum) and a control Newtonian fluid (45% glycerol) in a simplified model of the Fontan circulation. Particle image velocimetry was used to examine flow behavior at two different cardiac outputs and two caval blood flow distributions. Pressure and flow rates were measured at each inlet and outlet. Velocity, shear strain, and shear stress maps were derived from velocity data. Power loss was calculated from pressure, flow, and velocity data. Power loss was increased in all test conditions with xanthan gum vs. glycerol (mean 10 ± 2.9% vs. 5.6 ± 1.3%, p=0.032). Pulmonary blood flow distribution differed in all conditions, more so at low cardiac output. Caval blood flow mixing patterns and shear stress were also qualitatively different between the solutions in all conditions. We conclude that assuming blood to be a Newtonian fluid introduces considerable error into simulations of the Fontan circulation, where low-shear flow predominates.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Mechanics - B/Fluids - Volume 68, MarchâApril 2018, Pages 184-192
Journal: European Journal of Mechanics - B/Fluids - Volume 68, MarchâApril 2018, Pages 184-192
نویسندگان
Andrew L. Cheng, Niema M. Pahlevan, Derek G. Rinderknecht, John C. Wood, Morteza Gharib,