کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7139105 | 1462020 | 2018 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
High-sensitivity Sagnac-interferometer biosensor based on exposed core microstructured optical fiber
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A novel, high sensitivity Sagnac-interferometer biosensor based on exposed core microstructured optical fiber (ECF) has been designed and implemented in this paper. The exposed core fiber has noncircular symmetry and thus exhibits birefringence and can form a sensing element within a Sagnac loop interferometer. The exposed-core fiber design provides direct access to the evanescent field, allowing the measurement of bulk refractive index (RI) with a sensitivity of up to â3137â¯nm/RIU while maintaining the fiber's robustness. The sensor can also detect the localized refractive index changes at the fiber core's surface as the result of a biological binding event. We demonstrate the use of this sensor for label-free sensing of biological molecules by immobilizing biotin onto the fiber core as the probe to capture the target molecule streptavidin.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 269, 15 September 2018, Pages 103-109
Journal: Sensors and Actuators B: Chemical - Volume 269, 15 September 2018, Pages 103-109
نویسندگان
Xuegang Li, Linh V. Nguyen, Yong Zhao, Heike Ebendorff-Heidepriem, Stephen C. Warren-Smith,