A novel signal-on photoelectrochemical biosensor for detection of 5-hydroxymethylcytosine based on in situ electron donor producing strategy and all wavelengths of light irradiation

- A novel photoelectrochemical biosensor was developed for detection of 5-hydroxymethylcytosine.
- The biosensor was based on in situ electron donor producing strategy.
- The biosensor exhibited high sensitivity and excellent selectivity for 5-hydroxymethylcytosine.
- The biosensor uses all wavelengths of light irradiation to increase the utilization rate of light.