کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7145814 1462076 2015 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optofluidic chip for surface wave-based fluorescence sensing
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Optofluidic chip for surface wave-based fluorescence sensing
چکیده انگلیسی
An optofluidic chip based on a multilayered photonic crystal structure is employed for an efficient beaming of the emitted radiation in a fluorescent microarray assay. Upon a near-field coupling of fluorescent emitters to surface modes sustained by the photonic crystal, a significant portion of radiated energy is diffracted out-of-plane towards the collection optics. The improvement in fluorescence collection is experimentally demonstrated in an antibody-antigene immunoassay. As a result, a decrease of the limit of detection for labelled antigenes by a factor of about 40 is demonstrated to occur in a robust and reproducible way, with little or no optical alignment issues.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 215, August 2015, Pages 225-230
نویسندگان
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