کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7147416 1462098 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrochemical sensing of the genotoxicity of the micron LiFePO4 rice granule using a guanine biosensor based on LiFePO4/HCl/K2S2O8 System
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Electrochemical sensing of the genotoxicity of the micron LiFePO4 rice granule using a guanine biosensor based on LiFePO4/HCl/K2S2O8 System
چکیده انگلیسی
In order to investigate the genotoxicity of the micron LiFePO4 rice granule, an electrochemical biosensor based on determination of guanine (G) oxidative damage induced by the LiFePO4/HCl/K2S2O8 system was developed. In the LiFePO4/HCl/K2S2O8 system, the reaction of the micron LiFePO4 rice granule with HCl produced Fe2+, and the produced Fe2+ would further react with S2O82−, generating sulfate radical (SO4−) which could severely damage the guanine bases that was immobilized on a glassy carbon electrode (GCE) surface by electro-deposition. The square wave voltammetry (SWV) signal change of the guanine bases was used to monitor the guanine damage. The present work provided a simple electrochemical approach for screening the potential genotoxicity of particulate matters and chemicals in vitro, and it also had potential application in investigating some chemicals anti-oxidation property.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 192, 1 March 2014, Pages 234-238
نویسندگان
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