کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7148911 | 1462114 | 2013 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Enzyme-coated single ZnO nanowire FET biosensor for detection of uric acid
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Qualitative and quantitative detection of biological and chemical species is crucial in many areas, ranging from clinical diagnosis to homeland security. Due to the advantages of ultralow detection limit, label-free, fast readout and easy fabrication over the traditional detection systems, semiconductor nanowire based electronic devices have emerged as a potential platform. In this paper, we fabricated a single ZnO nanowire-based biologically sensitive field-effect transistors (bioFETs) for detection of different concentrations of uric acid solution at the same time. The addition of uric acid with the concentrations from 1Â pM to 0.5Â mM resulted in the electrical conductance changes of up to 227Â nS, and the response time turns out to be in the order of millisecond. The ZnO NW biosensor could easily detect as low as 1Â pM of the uric acid with 14.7Â nS of conductance increase, which implied that the detection limit of the biosensor can be as low as 1Â pM.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 176, January 2013, Pages 22-27
Journal: Sensors and Actuators B: Chemical - Volume 176, January 2013, Pages 22-27
نویسندگان
Xi Liu, Pei Lin, Xiaoqin Yan, Zhuo Kang, Yanguang Zhao, Yang Lei, Chuanbao Li, Hongwu Du, Yue Zhang,