کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7212948 | 1469395 | 2016 | 27 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nanoengineered bioactive 3D composite scaffold: A unique combination of graphene oxide and nanotopography for tissue engineering applications
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Nanoengineered bioactive 3D composite scaffold: A unique combination of graphene oxide and nanotopography for tissue engineering applications Nanoengineered bioactive 3D composite scaffold: A unique combination of graphene oxide and nanotopography for tissue engineering applications](/preview/png/7212948.png)
چکیده انگلیسی
A tissue engineering composite scaffold serves as a temporary skeleton to accommodate and stimulate new tissue growth. Here we report the development of a biodegradable porous composite scaffold made from the bioactive chitosan (CHN) and hyaluronic acid (HYA) with graphene oxide (GO). The CHN-HYA-GO composite scaffold was successfully prepared and compared with CHN-HYA composite scaffold and found that CHN-HYA-GO significantly improved mechanical and biological properties. Moreover, the CHN-HYA-GO composite scaffold possessed an adequate porosity, swelling behavior and degradation rate to mimic the extracellular matrix (ECM) with a favorable cell attachment and proliferation. The cells in contact with CHN-HYA-GO composite scaffolds remained viable and exhibited a high growth potential. Therefore the uniquely fabricated CHN-HYA-GO composite scaffolds possess great potential for various tissue engineering applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Composites Part B: Engineering - Volume 90, 1 April 2016, Pages 503-511
Journal: Composites Part B: Engineering - Volume 90, 1 April 2016, Pages 503-511
نویسندگان
Afeesh Rajan Unnithan, Chan Hee Park, Cheol Sang Kim,