Feedback Control with Hybrid Pump for Realistic Human Blood Pressure Reconstruction

Human blood pressure simulation is of particular interest for artificial blood vessel evaluation in regenerative medicine, and for endovascular surgery simulation to become more realistic. Conventional pumps do not offer a solution for the flow quality requirements; therefore we propose a hybrid pump that combines the best properties of lobe and piston pumps. Feedback control was applied to the hybrid pump, the system was tested using three different waveforms as reference. One of the waveforms is a polynomial approximation of pressure variation inside a coronary artery; when used a realistic human blood pressure simulation was produced. A scaffold for blood vessel regeneration was evaluated with the simulated human blood pressure.