AUTOMATIC MULTIMODAL REGISTRATION OF GATED CARDIAC PET, CT AND MR SEQUENCES

In this paper, we present an automatic multimodal registration method applied to gated PET, CT and MR images. CT images acquired on the same device as the PET ones are used to merge the anatomical MR and functional PET images. The registration process is divided in two steps: a 3D structure registration and a grey-levels registration. This approach enables global then local transformations. The structure registration uses a 3D biventricular heart model initialized on CT and MR data to define an optimal rigid transform. This global registration is then refined with the grey-levels step based on mutual information and free form deformations.