کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
724046 892361 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ANALYSIS OF METABOLIC NETWORKS OF SKELETAL MUSCLE CELL ENERGY METABOLISM
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مکانیک محاسباتی
پیش نمایش صفحه اول مقاله
ANALYSIS OF METABOLIC NETWORKS OF SKELETAL MUSCLE CELL ENERGY METABOLISM
چکیده انگلیسی

Network analysis was performed on the metabolic network of skeletal muscle cells where metabolites are denoted as nodes and reactions are denoted as connections. We also implemented an alternative approach that augments the metabolic network into an “interaction network” that represents influences that a certain metabolite can exert on others. With this novel method, key elements and modules of the system were identified with an emphasis on their regulatory function rather than just their contribution to material (carbon) flow within the pathways. We have utilized several different network analysis software packages to identify key metabolites, and motifs and investigated the modularity of these networks.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: IFAC Proceedings Volumes - Volume 40, Issue 4, 2007, Pages 25–30
نویسندگان
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