کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
725663 892547 2014 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Effect of Added Dead Space on Optimal Neuro-Muscular Drive and Respiratory Signals under Hypercapnia
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی کنترل و سیستم های مهندسی
پیش نمایش صفحه اول مقاله
The Effect of Added Dead Space on Optimal Neuro-Muscular Drive and Respiratory Signals under Hypercapnia
چکیده انگلیسی

The problem concerning the nature and the function of the dead space is of basic importance for the full comprehension of the respiratory physiology and pathophysiology. To study the effect of an imposed external dead space on the optimal respiratory control system, we simulated the optimal neuro-muscular drive and respiratory signals, including instantaneous airflow and lung volume profiles, with dead space loading under hypercapnia. The dead space measurement model by Gray was employed and the human respiratory control simulator based on an optimality hypothesis was implemented. The ventilatory control simulations were performed with external dead space loading of 0, 0.4 and 0.8 liters under rest condition (PICO2=0%) and CO2 inhalation of 3% to 7%. The optimization of the respiratory signals and model behavior of the optimal respiratory control under dead space loading and hypercapnia were verified and found to be in general agreement with experimental findings.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Applied Research and Technology - Volume 12, Issue 6, December 2014, Pages 1003–1013
نویسندگان
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