کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7294507 | 1474272 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular genetic contributions to socioeconomic status and intelligence
ترجمه فارسی عنوان
مشارکت ژنتیک مولکولی به وضعیت اجتماعی و اقتصادی
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کلمات کلیدی
نسل اسکاتلند، هوش تحصیلات، وضعیت اجتماعی و اقتصادی، ژنتیک،
موضوعات مرتبط
علوم انسانی و اجتماعی
روانشناسی
روانشناسی تجربی و شناختی
چکیده انگلیسی
Education, socioeconomic status, and intelligence are commonly used as predictors of health outcomes, social environment, and mortality. Education and socioeconomic status are typically viewed as environmental variables although both correlate with intelligence, which has a substantial genetic basis. Using data from 6815 unrelated subjects from the Generation Scotland study, we examined the genetic contributions to these variables and their genetic correlations. Subjects underwent genome-wide testing for common single nucleotide polymorphisms (SNPs). DNA-derived heritability estimates and genetic correlations were calculated using the 'Genome-wide Complex Trait Analyses' (GCTA) procedures. 21% of the variation in education, 18% of the variation in socioeconomic status, and 29% of the variation in general cognitive ability was explained by variation in common SNPs (SEs ~ 5%). The SNP-based genetic correlations of education and socioeconomic status with general intelligence were 0.95 (SE 0.13) and 0.26 (0.16), respectively. There are genetic contributions to intelligence and education with near-complete overlap between common additive SNP effects on these traits (genetic correlation ~ 1). Genetic influences on socioeconomic status are also associated with the genetic foundations of intelligence. The results are also compatible with substantial environmental contributions to socioeconomic status.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Intelligence - Volume 44, MayâJune 2014, Pages 26-32
Journal: Intelligence - Volume 44, MayâJune 2014, Pages 26-32
نویسندگان
Riccardo E. Marioni, Gail Davies, Caroline Hayward, Dave Liewald, Shona M. Kerr, Archie Campbell, Michelle Luciano, Blair H. Smith, Sandosh Padmanabhan, Lynne J. Hocking, Nicholas D. Hastie, Alan F. Wright, David J. Porteous, Peter M. Visscher,