کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
735515 1461717 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optical force on diseased blood cells: Towards the optical sorting of biological matter
ترجمه فارسی عنوان
نیروی نوری بر روی سلول های خون بیمار: در جهت مرتب سازی نوری ماده بیولوژیکی
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی برق و الکترونیک
چکیده انگلیسی


• We calculate optical forces on red blood cells infected by malaria.
• We studied how optical forces interact with biological samples.
• We show that optical force is very sensitive to the presence of a blood infection.
• We show that optical forces can be used for the treatment of biological diseases.

By employing a series of massively parallel ab-initio simulations, we study how optical forces act on biological matter subject to morphological disease. As a representative case study, we here consider the case of Plasmodium falciparum on red blood cells (RBC) illuminated by a monochromatic plane wave. Realistic parameters for the geometry and the refractive index are then taken from published experiments. In our theoretical campaign, we study the dependence of the optical force on the disease stage for different incident wavelengths. We show that optical forces change significantly with the disease, with amplitude variation in the hundreds of pN range. Our results open up new avenues for the design of new optical systems for the treatment of human disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Optics and Lasers in Engineering - Volume 76, January 2016, Pages 40–44
نویسندگان
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