In situ digital microfluidic conductance sampling

A digital microfluidic device architecture as well as a droplet position measurement algorithm based on in situ conductance sampling is presented. The system is implemented into a digital microfluidic multiplexer configuration, and it is shown to be an effective probe for the spatial distribution of conductive fluids in the structure. The conductance levels between differential combinations of perpendicular lower plate electrical address lines (x-channels) and upper plate electrical address lines (y-channels) are probed within the device, and a MATLAB-based algorithm is executed to extract the size and locations of microdrops within the system. Modeled results are compared to experimental measurements for the sampling algorithm and multiplexer device layout.