Utilizing a tripeptide conjugated fluorescent hybrid nanoparticles as a fluorescence sensor for the determination of copper ions

In this communication, the new, simple and sensitive fluorescent hybrid nanoparticles sensor has been designed for the copper ions detection. For this study, the fluorescent hybrid nanoparticles were synthesized by a single step approach and functionalized with tri peptide. And their size can range from about 70 to 75 nm in diameter. In the presence of copper ions, the imidazole rings of the histidine in tripeptide conjugated fluorescent hybrid nanoparticles can form six membered chelate rings complex, triggered energy transfer, and it leads fluorescence quenching. The results indicated that, minimum up to 0.5 μМ of copper ion caused the fluorescence quenching with excellent selectivity response over other interferences at the micro gram level and the quenching kinetics also discussed.