Dopamine detection with multilayer thin film prepared by using polyacrylic-acid-coated nano-ceria via layer-by-layer assembly

A multilayer thin film electrode has been prepared by using polyacrylic-acid coated nano-ceria and poly(diallyldimethylammonium chloride) via a layer-by-layer assembly method. The particles have been studied by the techniques of X-ray diffraction, transmission electron microscope, UV–vis absorption, and dynamic light scattering. The laminar growth of the thin film has been monitored by using UV–vis absorption spectra. The obtained multilayer film shows good sensitivity and selectivity for dopamine detection in the presence of excess ascorbic acid interferent using electrochemical method. We envision that this may provide a feasible way for in vivo detection of dopamine in the presence of excess interferents.